CPS 08 Prime interdental refills make cleaning between your teeth feel effortless. These ultrafine brushes glide smoothly into tight spaces to help reduce plaque, maintain gum health, and keep your breath fresh. Instructions: Insert carefully, move once in and out. Replace when bristles are worn. Compatible with all Curaprox click-system holders. At Curaprox, we believe oral care should be effective, safe and joyful. That's why our products are developed in Switzerland with a focus on prevention, softness and smart design.