Science-Based Nutrition Dietary Supplement Helps Support Joint Health and Flexibility Non-GMO Gluten Free Soy FreeDoctor's Best Glucosamine Chondroitin MSM provides three important nutrients which help support healthy joints and connective tissues: glucosamine, chondroitin and Methylsulfonyl-methane (MSM, from OptiMSM). Glucosamine sulfate helps joint health for joint lubrication, better joint movement and flexibility. Cartilage, composed of proteoglycans, is mainly located on bones, near the joints and consists primarily of collagen protein with side chains called chondroitin sulfate. MSM supplies bioavailable sulfur needed to support joint health, hair, skin, and nails. OptiMSM is purified via distillation for highest purity and consistency and is an excellent source of bioavailable sulfur. Helps support joint health and flexibility. Helps support and maintain the body's joints. Helps support overall health for hair, skin, and nails.