Get fast, powerful nasal congestion relief! In seconds, Original Maximum-Strength Afrin Nasal Spray can have you breathing better. No wonder it's the #1 doctor and pharmacist recommended nasal decongestant spray for congestion caused by colds and allergies. Afrin nasal spray: works for up to 12 hours, provides nasal congestion relief due to colds or allergies, and doesn't cause drowsiness.